Olopatadine Hydrochloride

Olopatadine Hydrochloride - General Information

Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from mast cells. It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.

Pharmacology of Olopatadine Hydrochloride

Used to treat allergic conjunctivitis (itching eyes), olopatadine inhibits the release of histamine from mast cells. It is a relatively selective histamine H1 antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.

Olopatadine Hydrochloride for patients

Olopatadine Hydrochloride Interactions

No information provided.

Olopatadine Hydrochloride Contraindications

PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% is contraindicated in persons with a known hypersensitivity to olopatadine hydrochloride or any components of PATANOL.

Additional information about Olopatadine Hydrochloride

Olopatadine Hydrochloride Indication: For the treatment of the signs and symptoms of allergic conjunctivitis.
Mechanism Of Action: Olopatadine Hydrochloride is a selective histamine H1 antagonist and binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Olopatadine Hydrochloride is devoid of effects on alpha-adrenergic, dopamine and muscarinic type 1 and 2 receptors.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Olopatadine
Synonyms: Not Available
Drug Category: Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihistamines; Histamine H1 Antagonists
Drug Type: Small Molecule; Approved

Other Brand Names containing Olopatadine: Olopatadine Hydrochloride; Patanol;
Absorption: Ophthalmic use of olopatadine usually does not produce measurable plasma concentrations.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: The mono-desmethyl and the N-oxide metabolites have been detected at low concentrations in the urine.
Half Life: 3 hours
Dosage Forms of Olopatadine Hydrochloride: Liquid Ophthalmic
Chemical IUPAC Name: 2-[(11Z)-11-(3-dimethylaminopropylidene)-6H-benzo[c][2]benzoxepin-2-yl]acetic acid
Chemical Formula: C21H23NO3
Olopatadine on Wikipedia: https://en.wikipedia.org/wiki/Olopatadine
Organisms Affected: Humans and other mammals